Many killed as deadly blasts rock Syria's coast
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Explosions hit the cities of Tartous and Jableh. Several of the blasts were suicide bombings, the UK-based Syrian Observatory for Human Rights said.
State media said packed bus stations and a hospital were among the targets.
Attacks of this scale are rare in these areas. A news agency linked to so-called Islamic State (IS) says the jihadist group was behind the attacks.
Syrian state TV said at least one suicide bomber on foot and a car bomber hit the bus station in Tartous.
The state news agency, Sana, said rockets hit the entrance of another bus station in Jableh, further north.